Akkal, Salah2025-04-172025-04-172021-12-13978-9931-9827-4-6http://dspace.univ-oeb.dz:4000/handle/123456789/21891The genus Centaurea is one of the largest genera of the sub-tribe Centaureinae including approx. 250 species (400 in an earlier classification). In Algerian flora, 45 species are present with 7 species localized in the Sahara. Algerian Centaurea species have been object of many phytochemical investigations, which showed their richness of bioactive secondary metabolites mainly flavonoids and sesquiterpene lactones. As results of pharmacological studies, various crude extracts and isolated compounds from Algerian Centaurea species have shown important biological activities, such as cytotoxic, antimicrobial, antioxidant, antiplasmodial activities. This study summarizes reports on chemical constituents from the Centaurea genus of the Asteraceae family growing in Algeria. A total of 158 different compounds has been reported from 26 species, and many of them are biologically active. Although ca. 45 species of Centaurea are distributed all over in Algeria, only 26 species were investigated. Future studies of those remaining species are desirable. To fully exploit the therapeutic value and utilize the resources of the species of this genus, their pharmacophylogenetics should be investigated further.enCentaurea; Phytochemistry; Biological activities.Image