Phytochemical study of lotus pusillus medik. (fabaceae)
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Date
2021-12-13
Journal Title
Journal ISSN
Volume Title
Publisher
University of Oum El Bouaghi
Abstract
The genus Lotus (tribe Loteae, family leguminosae) comprises about 120-130 species in the Algerian flora and is represented by fifteen species most of which occur in the Sahara. In folk medicine, plants of genus Lotus are used as contraceptives, prophylaxis and treatment of sexually transmitted disorders and peptic ulcers. Lotus pusillusMedik. named also Lotus halophilusBoiss has a good antimicrobial activity against Gram- positive, Gram-negative bacteria and fungi.
Phytochemical investigation of the aerial parts of Lotus pusillusMedik. Resulted in the isolation and identification of three known compounds. Liquid-Liquid fractionation of the crude extract followed by chromatographic purification resulted in the isolation of
2-hydroxybenzyl-3-D-glucopyranoside (1), maltol 3-0-6-0-benzoyl)-b-D-glucopyranoside (2) and a saponoside was identified as Azukisaponine V (3).
The molecular structures of isolated compounds were established by spectroscopic analysis particularly NMR 1D (H and 13C J-modulated) and 2D (COSY, HSQC J-modulated, HMBC, TOCSY and ROESY), mass spectrometry EI-MS and by comparison with literature data.
Description
Keywords
Lotus pusillus; Leguminosae; Maltol; Saponin