Synthesis, Characterization Of (ag-sno2) Nanoparticles And Investigation Of Its Antibacterial And Anti-biofilm Activities
| dc.contributor.author | Obeizi, Zahra | |
| dc.contributor.author | Benbouzid, Houneida | |
| dc.contributor.author | Bouarroudj, Tayeb | |
| dc.contributor.author | Benzaid, Chahrazed | |
| dc.contributor.author | Djahoudi, Abdelghani | |
| dc.date.accessioned | 2023-09-11T05:33:38Z | |
| dc.date.available | 2023-09-11T05:33:38Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Silver-doped tin oxide (Ag-doped SnO2) nanoparticles (NPs) were manufactured by using chemical co-precipitation method. The synthesized Ag-doped SnO2 nanoparticles were characterized by using X-Ray Diffraction (XRD) analysis, Dynamic Light Scattering (DLS), Fourier-transform infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDX) and Ultraviolet-visible (UV-Vis) spectroscopy. The antibacterial activity of the prepared Ag-SnO2 nanoparticles was carried by agar well diffusion method and determination of minimum inhibitory concentration against both Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae) and Gram-positive bacteria (Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis), anti-biofilm activity was investigated using 96-well microtiter plate method against Staphylococcus aureus and Pseudomonas aeruginosa. XRD Results confirm formation of Ag-doped SnO2 nanoparticles, the average grain size was found to be 23 nm; while DLS analysis indicates an average size around 29 nm. Morphological findings by SEM indicate dense particles with sponge-like microstructure that are uniformly organized irregularly, The EDX analysis confirms the purity of these nanoparticles with peaks of Ag, Sn, and O atoms. SnO2-Ag NPs were exhibited good antibacterial activity against all bacterial strains tested with maximum zone of inhibition of 27 ± 1.2 mm for S. aureus, the minimum inhibitory concentration values varied between 8 and 128 µg / ml. The significant percentage of biofilm inhibition was found 73.96% and 71.19% against S. aureus and P. aeruginosa biofilm, respectively. | ar |
| dc.identifier.issn | 2170-161X | |
| dc.identifier.issn | 2588-2082 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/15435 | |
| dc.language.iso | en | ar |
| dc.publisher | Oum-El-Bouaghi University | ar |
| dc.subject | Co-precipitation method | ar |
| dc.subject | Ag-SnO2 nanoparticles | ar |
| dc.subject | Antibacterial; Anti-biofilm | ar |
| dc.subject | Minimum inhibitory concentration | ar |
| dc.title | Synthesis, Characterization Of (ag-sno2) Nanoparticles And Investigation Of Its Antibacterial And Anti-biofilm Activities | ar |
| dc.type | Article | ar |