Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L
No Thumbnail Available
Date
2012
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Abstract
Background: Several species of the genus Launaea are used in folk medicine such as in bitter stomachic, skin
diseases, and reported to have antitumor, insecticide, and cytotoxic activities. The antimicrobial activities of
coumarin constituents and the neuropharmacological properties have been investigated as well. In this study, the
chemical composition of essential oils from Launaea resedifolia L. has been identified using the ordinary GC-MS
technique to reveal the presence of 19 compounds dominated by dioctyl phthalate. Moreover, the antibacterial
activity of the crude oil has been carried out using disk diffusion method against seven bacteria strains.
Results: Nineteen compounds of essential oil of L. resedifolia L. were identified, representing 86.68% of the total oil.
The compounds were identified by spectral comparison to be mainly esters, alcohols, ketones, and terpenes. The
principal constituents are dioctyl phthalate (39.84%), Decanoic acid, decyl ester (12.09%), 11-Octadecenal (11.24%),
and Eucalyptol (07.31%), while others were present in relatively small amounts. As far as antibacterial essays are
concerned, it was found that the oils are active against most of the tested bacterial strains.
Conclusion: A major constituent in visible parts was Dioctyl phthalate (39.84%) and the yield of essential oils was
0.9%. These extracts reveal in vitro antibacterial activity on the studied bacterial, confirmed by the inhibition zone
diameter ranging from 11 to 37 mm and a MIC value between 0.09 and 0.69 depending on the microorganism
being tested.
Description
Keywords
Chemical composition, Antibacterial activity, Essential oils, Launaea resedifolia