Antimicrobial activity of polyphenol-rich extracts from solanum nigrum leaves
Loading...
Date
2021-12-13
Journal Title
Journal ISSN
Volume Title
Publisher
University of Oum El Bouaghi
Abstract
Polyphenols are molecules found specifically in the plant kingdom. Polyphenols, mainly flavonoids, are known by their various biological effects. They have anti-carcinogenic, anti-inflammatory, anti-atherogenic, analgesic and antimicrobial activities. The objective of this study is to assess the content of polyphenols and flavonoids, and to evaluate the antibacterial activity of different phenolic compounds from a wild plant, Solanumnigrum L, which grows in the Adrar region. Our results show that Solanumnigrum L contains an average amount of polyphenols estimated at 10.74 mg GAE/g DM. Moreover, the fractionation of the total flavonoid available in the aqueous phase, with ethyl acetate followed by n-butanol, revealed that n- butanolphase contains the highest rate (48% of total flavonoids). The antibacterial activity showed the effectiveness of all extracts against Escherichia coli and prominently against Staphylococcus aureus. However, Clostridiumgenusseemed to be resistantvis-a-vis all tested extracts. Thus, Solanumnigrum leaves could be used to treat some infectious diseases.
Description
Keywords
Solanumnigrum L; Polyphenols; Flavonoids; Antimicrobial activity.