Browsing by Author "Rhouati, Salah"
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Item Chemical composition and antibacterial activity of the essential oils of Ferula vesceritensis Coss et Dur. leaves, endemic in Algeria(Springer, 2012) Zellagui, Amar; Gherraf, Noueddine; Rhouati, SalahBackground: The biological importance of members of genus Ferula promoted us to investigate the leaves of Ferula vesceritensis Coss et Dur. (endemic plant) previously not investigated. This study presents the chemical composition and antibacterial activities of the hydrodistilled oils. Results: Volatile components of the leaves of F. vesceritensis have been studied by gas chromatography–mass spectrometry to afford 23 compounds. The major components were found to be 5,9-tetradecadiyne (24.72%), germacrene D (24.51%), farnesene (8.57%), and α-bisabolene (8.57%). The antimicrobial activities of the essential oils were evaluated by disk diffusion method and tested against Gram-positive and Gram-negative bacteria. The volatile oil showed a strong antibacterial activity against Staphylococcus aureus, Escherichia coli, and Klebsiella pneumonia. Conclusions: These results reinforce the previous studies showing that the genus Ferula is considered as a good source of essential oils. The results presented here can be considered as the first information on the antimicrobial properties of F. vesceritensis.Item Chemical constituents and antimicrobial activity of essential oils of Ammodaucus leucotricus(Elsevier, 2013) Gherraf, Noureddine; Zellagui, Amar; Kabouche, Azeddine; Lahouel, Mesbah; Salhi, Ramdane; Rhouati, SalahAmmodaucus belongs to the family Apiaceae (Umbelliferae), subfamily Apioideae, trib Caucalideae, and comprises one species in Algeria (Quezel and Santa, 1962). The biological importance of members of this genus promoted us to reinvestigate the volatile constituents of the fruits of Ammodaucus leucotricus Coss. et Dur., and to carry out a biological study as far as the antibacterial activity is concerned. The present work deals with the chemical composition and antibacterial activities of the hydrodistilled oils. After extraction, the oil was analyzed by gas chromatography–mass spectrometry to afford 14 components. The major components were found to be, 1-cyclohexene-1-carboxaldehyde (56.40%), D-limonene (28.82%), and 2-pentanone- 4-hydroxy-4-methyl (5.73%). Moreover, the antimicrobial activities of the volatile oils were evaluated by disk diffusion method against Gram-positive and Gram-negative bacteria. The results showed a strong antibacterial activity against Staphylococcus aureus, Escherichia coli and Klebsiella pneumonia.Item Chemical constituents of the roots of Algerian Bunium incrassatum and evaluation of its antimicrobial activity(Elsevier, 2011) Bousetla, Ahlem; Zellagui, Amar; Derouiche, Kamel; Rhouati, SalahIn this study we investigated the chemical composition of the roots of Bunium incrassatum growing in Algeria, two coumarins, b-sitosterol, sucrose and oleic acid were isolated from methylene chloride:methanol (1/1) extract of the roots of this species. Furthermore, antimicrobial activity of the crude extract was evaluated using agar diffusion method. The antimicrobial results showed that the crude extract had a great potential antimicrobial activity against all the test microorganisms especially fungal strains.