علوم وتكنولوجيا

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Browsing علوم وتكنولوجيا by Author "Abidi, A."

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    Role of hydroxypropylmethylcellulose (HPMC 4000) in the protection of the polymorphs of piroxicam extended release tablets
    (Springer, 2013) Merah, A.; Abidi, A.; Chaffai, N.; Bataille, B.; Gherraf, N.
    The present study deals with the influence of hydroxypropylmethylcellulose 4000 in the protection of Piroxicam polymorphs which could appear during the processes of formulation of extended release tablets. The physico-chemical tests and the dissolution profiles of polymorphs and tablets showed that the metolose incorporated in the tablets at a rate equivalent to 5% could possibly act doubly; initially by protecting the piroxicam polymorphism transition (form II) during compression, then modulating its in vitro release (extended release).