1er séminaire national sur la biothéchnologie des plantes médicinales et leur implication dans l'industrie pharmaceutique et alimentaire (BPMIPA) le 13-14 Décembre 2021

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Browsing 1er séminaire national sur la biothéchnologie des plantes médicinales et leur implication dans l'industrie pharmaceutique et alimentaire (BPMIPA) le 13-14 Décembre 2021 by Author "Akkal, Salah"

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    Chemical composition and antibacterial activity of essential oil of ferula lutea (poir) maire, aerial parts (fruits, umbels, stems and leaves) from setif (algeria).
    (University of Oum El Bouaghi, 2021-12-13) Rahmouni, Malika; Laouer, hocine,; Flamini, Guido; Akkal, Salah; Djermane, Nadia
    Discovery of several natural products, isolated from medicinal plants, contribute to avoid the resistance of pathogenic microorganisms to antibiotics. This work aims to study the chemical composition as well the effects of essential oils (EOS), from Ferula lutea (Apiaceae) aerial parts (Fruits, umbels, Stems and leaves) from Amoucha in Sétif, Eastern Algeria.The essential oil was obtained by hydrodistillation and analyzed by gas-chromatography-mass spectrometry (GC/MS). The antibacterial activity of the essential oils is evaluated by disk diffusion method (NCCLS) and tested against gram-positive (B. cereus, S. aureus) and gram-negative (E. coli, P. mirabilis) bacteria. The yields of the different parts of this plant (fruits, stems, umbels and leaves) were (2.484, 0.025, 1.248 and 0.213%) respectively. The main components of F. lutea EOS were 6-3-carene, a- pinene, limonene, cis-chrysanthenyl acetate and 2-3-6-trim é thylbenzaldehyde:(27,4-30,2-33,1-20,6):(16,5- 27,9-19,6-16,1);(5,2-9,5-7,8-10,5); ( 14,9-8,6-6,9-9,5) and(14,4-3,2-9,6-11,7 %). The screening of the antimicrobial effect revealed that the HE flowers showed the highest activity against all Gram-negative (E. coli, P. mirabilis) and Gram-positive (B. cereus, S. aureus) strains, the diameters of the inhibition zones are (13±2.12 - 12.83 ± 0.28) and (16.33 ± 0.76-10.16 ± 0.57) respectively. The results of IMC of EO flowers showed that Bacillus cereus is the most sensitive with IMC 3.33 mg/ml.
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    Phytochemistry and biological activities of Algerian
    (University of Oum El Bouaghi, 2021-12-13) Akkal, Salah
    The genus Centaurea is one of the largest genera of the sub-tribe Centaureinae including approx. 250 species (400 in an earlier classification). In Algerian flora, 45 species are present with 7 species localized in the Sahara. Algerian Centaurea species have been object of many phytochemical investigations, which showed their richness of bioactive secondary metabolites mainly flavonoids and sesquiterpene lactones. As results of pharmacological studies, various crude extracts and isolated compounds from Algerian Centaurea species have shown important biological activities, such as cytotoxic, antimicrobial, antioxidant, antiplasmodial activities. This study summarizes reports on chemical constituents from the Centaurea genus of the Asteraceae family growing in Algeria. A total of 158 different compounds has been reported from 26 species, and many of them are biologically active. Although ca. 45 species of Centaurea are distributed all over in Algeria, only 26 species were investigated. Future studies of those remaining species are desirable. To fully exploit the therapeutic value and utilize the resources of the species of this genus, their pharmacophylogenetics should be investigated further.